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MedChemExpress 1 abt
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
1 Abt, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher 2 2 azino bis 3 ethylbenzothiazoline 6 sulfonic acid abts
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
2 2 Azino Bis 3 Ethylbenzothiazoline 6 Sulfonic Acid Abts, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress abt 199
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
Abt 199, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress abt
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
Abt, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress abt 263
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
Abt 263, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Abbott Laboratories abt 737
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
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Nanjing Jiancheng Bioengineering Research Institute Co Ltd 2 2 azino bis 3 ethylbenzothiazoline 6 sulphonic acid diammonium salt abts
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
2 2 Azino Bis 3 Ethylbenzothiazoline 6 Sulphonic Acid Diammonium Salt Abts, supplied by Nanjing Jiancheng Bioengineering Research Institute Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/abt/2+2+6+azino+bis3+ethylbenzothiazoline+sulfonic/pmc13265830-43-19-10
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Shanghai Macklin Biochemical abts
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
Abts, supplied by Shanghai Macklin Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Macklin Inc abts method
(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole <t>(1-ABT)</t> or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.
Abts Method, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole (1-ABT) or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.

Journal: PLOS Biology

Article Title: Heme acts as a metabolic brake on erebosis in the Drosophila gut

doi: 10.1371/journal.pbio.3003942

Figure Lengend Snippet: (A) Feeding of CYP P450 inhibitors 1-Aminobenzotriazole (1-ABT) or piperonylbutoxide (PBO) does not restore the inhibition of erebosis by heme. 1-ABT with Ho RNAi and PBO with Mrp5 RNAi result in >50% class0 and no class2, which is similar to Ho RNAi or Mrp5 RNAi with DMSO. (B) ROS levels are not increased by Mrp5 RNAi . Using hsFLP system, Mrp5 RNAi was induced only in GFP+ cells. ROS probe dihydroethidium (DHE, magenta) is not changed in GFP+ Mrp5 RNAi cells (dashed line). (C) Ho RNAi or Mrp5 RNAi does not increase signals of lipid peroxide probe Liperfluo (green), while bleomycin increases them. (D) Feeding of a reducing agent N-acetylcysteine (NAC) does not increase erebosis. P values were calculated using Fisher’s exact test (A, D) and adjusted with the Benjamini–Hochberg method (D). Scale bars, 50 μm.

Article Snippet: Flies were fed with standard food with 15 μM 1-ABT (MedChemExpress HY-103389) or PBO (MedChemExpress HY-B1198) at 30 °C for 7 days.

Techniques: Inhibition